IN VITRO AND IN VIVO NEUTRALIZING POTENTIAL OF TERMINALIA ARJUNA BARK EXTRACT AGAINST NAJA NAJA VENOM
نویسندگان
چکیده
منابع مشابه
In Vitro and in Vivo Neutralizing Potential of Terminalia Arjuna Bark Extract against Naja Naja Venom
Envenoming’s by snake bite to involve medical emergencies and its clinical management is by the administration of antivenom. As antivenom was reported to induce early or late adverse reactions against human beings, snake venom neutralizing potential for aqueous bark of Terminalia arjuna extract was tested for the present research by in vitro and in vivo methods against Naja naja venom. In vitro...
متن کاملIn vitro and in vivo Evaluation of CYP1A Interaction Potential of Terminalia Arjuna Bark
Terminalia arjuna Wight and Arn. (Combretaceae) is a tree having an extensive medicinal potential in cardiovascular disorders. Triterpenoids are mainly responsible for cardiovascular properties. Aqueous, hydroalcoholic and alcoholic extract of T. arjuna, arjunic acid and arjungenin were examined for their potential to inhibit CYP1A enzyme in rat and human liver microsomes. IC50 values of aqueou...
متن کاملCharacterisation of Polyphenols in Terminalia arjuna Bark Extract
The bark of Terminalia arjuna is known for its heart-health benefits in ayurvedic literature. This has been further supported by in vivo studies on animal and human volunteers. But there is no detailed study on identification of the active ingredients such as polyphenols. Polyphenols possesses antioxidant properties and are well-known health actives, it is important to characterise polyphenols ...
متن کاملNaja naja atra Venom Protects against Manifestations of Systemic Lupus Erythematosus in MRL/lpr Mice
Systemic lupus erythematosus (SLE) is an autoimmune disease and effective therapy for this pathology is currently unavailable. We previously reported that oral administration of Naja naja atra venom (NNAV) had anti-inflammatory and immune regulatory actions. We speculated that NNAV may have therapeutic effects in MRL/lpr SLE mice. Twelve-week-old MRL/lpr mice received oral administration of NNA...
متن کاملCHARACTERIZATION OF AN ANTICOAGULANT AGENT IN THE VENOM OF IRANIAN COBRA (NAJA NAJA OXIANA).
Snake venoms contain a rich variety of factors which affect blood coagulation. There have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the Iranian cobra, although a procoagulant factor has been described. In this study an anticoagulant factor has been purified from the venom of Naja naja oxiana using gel filtrat...
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ژورنال
عنوان ژورنال: International Journal of Research in Ayurveda & Pharmacy
سال: 2017
ISSN: 2277-4343
DOI: 10.7897/2277-4343.08271